Abstract The BOYS physics of complex systems stands to greatly benefit from the qualitative changes in data availability and advances in data-driven computational methods.Many of these systems can be represented by interacting degrees of freedom on inhomogeneous graphs.However, the lack of translational invariance presents a fundamental challenge t
Phosphorylation and Dephosphorylation of Tau Protein During Synthetic Torpor
Tau protein is of primary importance for many physiological processes in neurons, where it affects the dynamics of the microtubule system.When hyperphosphorylated (PP-Tau), Tau monomers detach from microtubules and tend to aggregate firstly in oligomers, and then in neurofibrillary tangles, as it occurs in a group of neurodegenerative disorders nam
Hybrid lentivirus-phiC31-int-NLS vector allows site-specific recombination in murine and human cells but induces DNA damage.
Gene transfer allows transient Crochet Notions or permanent genetic modifications of cells for experimental or therapeutic purposes.Gene delivery by HIV-derived lentiviral vector (LV) is highly effective but the risk of insertional mutagenesis is important and the random/uncontrollable integration of the DNA vector can deregulate the cell transcrip